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Alomone Labs polyclonal rabbit anti p2x 7 receptor antibody
Effects of day in culture and of treatments with EGF and epinephrine on the expression of the <t> P2X 7 </t> receptor
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Millipore p2 x 7 receptor antagonist a 438,079
Effects of day in culture and of treatments with EGF and epinephrine on the expression of the <t> P2X 7 </t> receptor
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Graphical abstract of the modulatory effect of ATP on the expression of the pro-fibrotic genes CTGF and TIMP-1 in rat kidney Binding of ATP to P2 X 7R triggers a rapid activation of latent TGF-β which in turn activates TGF-β receptors resulting in Smad phosphorylation. Then, phosphorylated Smads (p-Smad2/3) form a complex with smad-4 which moves into the nucleus and stimulate the expression of the profibrotic genes CTGF and TIMP-1. Adenosine 5′-triphosphate (ATP); The purinergic <t>P2</t> <t>X</t> <t>7</t> receptor (P2 X 7R); A specific antagonist of P2 X 7 receptor (A 438,079); Connective tissue growth factor (CTGF); Tissue inhibitors of matrix metalloproteinases-1 (TIMP-1); Transforming growth factor-β (TGF-β); Transforming growth factor-β receptor I (TGF-βRI); Transforming growth factor-β receptor II (TGF-βRII).
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Pfizer Inc p2x 7 −/
Graphical abstract of the modulatory effect of ATP on the expression of the pro-fibrotic genes CTGF and TIMP-1 in rat kidney Binding of ATP to P2 X 7R triggers a rapid activation of latent TGF-β which in turn activates TGF-β receptors resulting in Smad phosphorylation. Then, phosphorylated Smads (p-Smad2/3) form a complex with smad-4 which moves into the nucleus and stimulate the expression of the profibrotic genes CTGF and TIMP-1. Adenosine 5′-triphosphate (ATP); The purinergic <t>P2</t> <t>X</t> <t>7</t> receptor (P2 X 7R); A specific antagonist of P2 X 7 receptor (A 438,079); Connective tissue growth factor (CTGF); Tissue inhibitors of matrix metalloproteinases-1 (TIMP-1); Transforming growth factor-β (TGF-β); Transforming growth factor-β receptor I (TGF-βRI); Transforming growth factor-β receptor II (TGF-βRII).
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Glaxo Smith p2x 7 −/− mouse
Graphical abstract of the modulatory effect of ATP on the expression of the pro-fibrotic genes CTGF and TIMP-1 in rat kidney Binding of ATP to P2 X 7R triggers a rapid activation of latent TGF-β which in turn activates TGF-β receptors resulting in Smad phosphorylation. Then, phosphorylated Smads (p-Smad2/3) form a complex with smad-4 which moves into the nucleus and stimulate the expression of the profibrotic genes CTGF and TIMP-1. Adenosine 5′-triphosphate (ATP); The purinergic <t>P2</t> <t>X</t> <t>7</t> receptor (P2 X 7R); A specific antagonist of P2 X 7 receptor (A 438,079); Connective tissue growth factor (CTGF); Tissue inhibitors of matrix metalloproteinases-1 (TIMP-1); Transforming growth factor-β (TGF-β); Transforming growth factor-β receptor I (TGF-βRI); Transforming growth factor-β receptor II (TGF-βRII).
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Serono p2x 7 r
Graphical abstract of the modulatory effect of ATP on the expression of the pro-fibrotic genes CTGF and TIMP-1 in rat kidney Binding of ATP to P2 X 7R triggers a rapid activation of latent TGF-β which in turn activates TGF-β receptors resulting in Smad phosphorylation. Then, phosphorylated Smads (p-Smad2/3) form a complex with smad-4 which moves into the nucleus and stimulate the expression of the profibrotic genes CTGF and TIMP-1. Adenosine 5′-triphosphate (ATP); The purinergic <t>P2</t> <t>X</t> <t>7</t> receptor (P2 X 7R); A specific antagonist of P2 X 7 receptor (A 438,079); Connective tissue growth factor (CTGF); Tissue inhibitors of matrix metalloproteinases-1 (TIMP-1); Transforming growth factor-β (TGF-β); Transforming growth factor-β receptor I (TGF-βRI); Transforming growth factor-β receptor II (TGF-βRII).
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Dawley Inc p2x 7
Graphical abstract of the modulatory effect of ATP on the expression of the pro-fibrotic genes CTGF and TIMP-1 in rat kidney Binding of ATP to P2 X 7R triggers a rapid activation of latent TGF-β which in turn activates TGF-β receptors resulting in Smad phosphorylation. Then, phosphorylated Smads (p-Smad2/3) form a complex with smad-4 which moves into the nucleus and stimulate the expression of the profibrotic genes CTGF and TIMP-1. Adenosine 5′-triphosphate (ATP); The purinergic <t>P2</t> <t>X</t> <t>7</t> receptor (P2 X 7R); A specific antagonist of P2 X 7 receptor (A 438,079); Connective tissue growth factor (CTGF); Tissue inhibitors of matrix metalloproteinases-1 (TIMP-1); Transforming growth factor-β (TGF-β); Transforming growth factor-β receptor I (TGF-βRI); Transforming growth factor-β receptor II (TGF-βRII).
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Image Search Results


Effects of day in culture and of treatments with EGF and epinephrine on the expression of the  P2X 7  receptor

Journal:

Article Title: Epidermal Growth Factor Facilitates Epinephrine Inhibition of P2X 7 -Receptor-Mediated Pore Formation and Apoptosis: A Novel Signaling Network

doi: 10.1210/en.2004-1026

Figure Lengend Snippet: Effects of day in culture and of treatments with EGF and epinephrine on the expression of the P2X 7 receptor

Article Snippet: Expression of the P2X 7 receptor protein was analyzed using the Alomone polyclonal rabbit anti-P2X 7 receptor antibody as the primary antibody.

Techniques: Expressing

Graphical abstract of the modulatory effect of ATP on the expression of the pro-fibrotic genes CTGF and TIMP-1 in rat kidney Binding of ATP to P2 X 7R triggers a rapid activation of latent TGF-β which in turn activates TGF-β receptors resulting in Smad phosphorylation. Then, phosphorylated Smads (p-Smad2/3) form a complex with smad-4 which moves into the nucleus and stimulate the expression of the profibrotic genes CTGF and TIMP-1. Adenosine 5′-triphosphate (ATP); The purinergic P2 X 7 receptor (P2 X 7R); A specific antagonist of P2 X 7 receptor (A 438,079); Connective tissue growth factor (CTGF); Tissue inhibitors of matrix metalloproteinases-1 (TIMP-1); Transforming growth factor-β (TGF-β); Transforming growth factor-β receptor I (TGF-βRI); Transforming growth factor-β receptor II (TGF-βRII).

Journal: Purinergic Signalling

Article Title: P2 X 7 receptor is a critical regulator of extracellular ATP-induced profibrotic genes expression in rat kidney: implication of transforming growth factor-β/Smad signaling pathway

doi: 10.1007/s11302-023-09977-4

Figure Lengend Snippet: Graphical abstract of the modulatory effect of ATP on the expression of the pro-fibrotic genes CTGF and TIMP-1 in rat kidney Binding of ATP to P2 X 7R triggers a rapid activation of latent TGF-β which in turn activates TGF-β receptors resulting in Smad phosphorylation. Then, phosphorylated Smads (p-Smad2/3) form a complex with smad-4 which moves into the nucleus and stimulate the expression of the profibrotic genes CTGF and TIMP-1. Adenosine 5′-triphosphate (ATP); The purinergic P2 X 7 receptor (P2 X 7R); A specific antagonist of P2 X 7 receptor (A 438,079); Connective tissue growth factor (CTGF); Tissue inhibitors of matrix metalloproteinases-1 (TIMP-1); Transforming growth factor-β (TGF-β); Transforming growth factor-β receptor I (TGF-βRI); Transforming growth factor-β receptor II (TGF-βRII).

Article Snippet: The P2 X 7 receptor antagonist, A 438,079 was from Sigma-aldrich Co. (St. Louis, MT, USA).

Techniques: Expressing, Binding Assay, Activation Assay